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We customize your future clinical trials in Oncology with our PDX models

 

OncoFactory is a biotech offering unique, innovative and predictive patient-derived xenograft models in oncology

We create replicas of patient tumors in a fast and powerful in vivo model, suited for all types of cancers. Tumors are  analyzed using 3D imaging. Replicas can be collected back for a range of molecular analysis.

Using our technological platform we can:

– evaluate the efficacy of your therapeutic candidates on representative samples of the population of patients

– help you in the design of combi-therapies through a dedicated program integrating analysis of tumor responses to the candidate therapy and characterization of candidate therapy-induced activated signaling pathways

– characterize the mechanisms of action of your candidate therapies

-identify biomarkers to stratify the population of patients, predict the resistance

Take advantage of our services for:

 – Discovery and early screening

 – Preclinical efficacy and lead validation

 – Translational biomarker Discovery

 – Mimic of conditions of clinical trials

 – Characterization of the mode of action of your candidate molecules

Cancer types successfully replicated in our model:

Breast cancer
Melanoma
Prostate cancer
Pancreatic cancer
Lung cancer
Liver cancer
Glioma
Glioblastoma
Neuroblastoma
Germ Cell tumor

Oncofactory can design custom-made models and experimental programs adapted to the needs and specifities of clients. Please  contact  us  to  discuss  your  project.

Events

Oncofactory presents a poster at the 4th international cancer symposium in Lyon
Oncofactory presents a poster at the 4th international cancer symposium in Lyon
OncoFocarory presents the AVI-PDX™ model as a novel and powerful technology for the creation of preclinical models of cancers.
Partnership with Calym Carnot Institute
Partnership with Calym Carnot Institute
July, 2019th   OncoFactory announces the starting of a R&D program dedicated to the setting of AVI-PDX models of Lymphoma. This program will be conducted…
Oncofactory presents its technology at Matwin Convention in Bordeaux
Oncofactory presents its technology at Matwin Convention in Bordeaux
Dr Frederic Berget was invited to present the AVI-PDX™ model to the 5th edition of the Matwin  European Partnering Convention dedicated to open innovation, collaborative…

Scientific papers

51th meeting of the European Pancreatic Club in Bergen
51th meeting of the European Pancreatic Club in Bergen
June 2019th   OncoFactory made an oral presentation at the 51th meeting of the European Pancreatic Club in Bergen (Norway) to report the development of…
Selected publications of the scientific founders since 2010
Selected publications of the scientific founders since 2010
Delloye-Bourgeois C, Bertin L, Thoinet K, Jarrosson L, Kindbeiter K, Buffet T, Tauszig-Delamasure S, Bozon M, Marabelle A, Combaret V, Bergeron C, Derrington E, Castellani…
An avian embryo to model Neuroblastoma
An avian embryo to model Neuroblastoma
In its October 2017 edition, the international journal Cancer Cell publishes the work of Dr. Céline Delloye-Bourgeois and Dr. Valérie Castellani, co-founders of OncoFactory. This…